Inactivating mutations of proapoptotic Bad gene in human colon cancers
نویسندگان
چکیده
منابع مشابه
Inactivating mutations of proapoptotic Bad gene in human colon cancers.
Evidence exists that deregulation of apoptosis is involved in the mechanisms of cancer development, and the somatic mutations of apoptosis-related genes have been reported in human cancers. Bcl-XL/Bcl-2-associated death promoter (Bad), a proapoptotic member of Bcl-2 family, plays an important role in the intrinsic apoptosis pathway. To explore the possibility that the genetic alterations of Bad...
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ژورنال
عنوان ژورنال: Carcinogenesis
سال: 2004
ISSN: 1460-2180,0143-3334
DOI: 10.1093/carcin/bgh145